Two Cases of Intrathecal Baclofen Pump "Pocket Fill" Resulting in Baclofen Overdose-Two Cases of Intrathecal Baclofen Pump "Pocket Fill" Resulting in Baclofen Overdose

Two Cases of Intrathecal Baclofen Pump "Pocket Fill" Resulting in Baclofen Overdose

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Video Summary

The presenter discusses a case series involving two patients who experienced overdose symptoms after refilling their intrathecal baclofen pumps. Normally, pocket fills result in withdrawal symptoms, but these cases were unique. The presenter explains the process of intrathecal baclofen delivery through a pump and catheter, and how the pump reservoir is refilled. The first case involved a 44-year-old female who experienced progressive numbness and weakness after a routine refill. The second case involved a 59-year-old male who became unresponsive four hours after a pump refill. Both patients required hospitalization and dialysis to recover. The presenter suggests that baclofen may have crossed the blood-brain barrier, leading to overdose symptoms. Overall, pocket fills are rare but serious complications of baclofen pumps.

Keywords

case series

intrathecal baclofen pumps

overdose symptoms

pocket fills

blood-brain barrier